5e Diseases

Diseases

See Also: 5e Diseases

Diseases	Summary
Abyssal Flames	Your soul is being consumed
Acid Plague	A infection of sores that contain acid
Acne	A disease which makes the skin erupt with pus and repel everyone around the afflicted.
Alkali Fever	If the air smells of metal, run.
An Arsonist's Curse	When too many things burn, you do, too.
Arachnomania	And you thought the Drider was the most monstrous spider out there?
Black Fly Filth Fever	A disease spread by flies that causes the afflicted to slowly rot
Bleeding	Swords don't just hurt you, silly! They make you BLEED!
Blowfat Syndrome	Sickening disease that makes the afflicted bigger and fatter.
Botularia	A mind-devouring infection characterized by moldy skin and bad taste. The infectious microform of the botularia.
Burning Thingy	The tingling becomes a sudden pain between your legs...
Cheese Touch	A horrifying affliction that turns one into an outcast.
Coddrow	You now have a sudden and unnatural fear of sharp objects.
Coping Mechanism: Shutdown	A form of PTSD.
Creeping Oak	Slowly turns you into a tree.
Dance Fever	A sickness that causes those afflicted to dance uncontrollably
Dead Frog Disease	This disease is a deadly disease only found in wet tombs or deep in sewers
Death's Touch	A cold seeps into your very bones and soul, enclosing an icy and deathly grip.
Dementia	A horrible... sad disease and a.. uh... what else was there?
Demonify	Things are take a turn for the demonic...
Dimensional Hiccups	Dimensional instability manifesting in the form of hiccups.
Dracoshift Flu	slowly and painfully turns one into a dragon. Hic Sunct Draconis.
Dread Esqueleto	A dangerous disease that turns the infected into living bone.
Flame Venom	Avoid the Dragon's tooth.
Fluvium	An infection that causes fever and intense, lucid dreams. The infectious microform of the Fluvium.
Fog of the Mind	A disease from a a mushroom spore, which causes your mind to fog.
Food Poisoning	Have you ever asked your players "why did you eat that!?"
Form Reconstruction	A disease which causes infected to melt and spread the disease to others.
Foulmonella	A waterborne disease that stinking slime secretion and indifference. The infectious microform of the foulmonella.
Glitched	The channeling of ones Ḡ̯͍̣̠̩̇̒̀̊ͅl͍̖̝ͨ͗̏i̜̦̗̇ͤ̎͌͌̎t̤̣ͨͨ̔̄̀̓̂c̭̖ͣ̇͒ͥͦh̐ͦ̏ into another host.
Hanahaki Disease	Please...I beg you...love me back...
Impassioned Perception	Sense the emotions of others around you
Infected Heart	A disease which spreads infection through heartbeats.
Infection	As wounds begin to fester, death becomes ever-present.
Innanonfeall	Your internal organs swell, harming you when you move.
Ironrot	A disease that slowly turns one into a ferrous material
Ligma	A rare disease often affecting Fortnite streamers.
Maiden's Blood Fever	Be careful where you step or you'll be growing some breasts.
Miners Plague	Miners' Plague is a disease that comes from mushrooms from the Underdark or similar locations. The Miners' Plague slowly infects the host until it forms sacks of pollen on it, then taking over it's mind making the target explode in a populated area killing the host and spreading the Plague.
Morph Fever	A disease coming across from overuse of polymorph or from other magic sources.
Necrotic Disease	A death dog is deadly indeed; one bite is all they need.
Night Terrors	A mental disease causing extreme nightmares that prevent the player from getting a full night's rest.
Night Terrors; Persistent Variety	Night Terrors with no treatment, ones you had even before joining the party.
Nyctodiafora	You ain’t seen nothin’ yet, son!
Otug's Disease	A disease which afflicts you with mindless, uncontrollable rage.
Paranoia	Paranoia is a mental condition which causes you to be irrationally suspicious towards others, often to the point of delusion.
Plague of Thorns	Grow spikes, lose your hands
Pneumania	A disease causing chills and fear. The infectious microform of the [Pneumania (5e Creature)|pneumania]].
Radiation Poisoning	Sickness and afflictions caused by exposure to radiation.
Random Change	Is this what they mean by "having an identity crisis"?
Rigor Vitalis	A disease which causes bodily stiffness in the living.
Rotscale	Flaky skin and an infection of the eyes can turn one into the stuff of nightmares.
Sailor's Strait	You'll be dying, you'll be crying, early in the morning.
Salmon-ella	You puke fish.
Scale Sickness/Dragon Lycanthropy	This is much less awesome than it sounds, I promise.
Scrabies	An insect-born disease characterized by an itching rash and hallucinatory infestation. The infectious microform of the scrabies.
Shadowflame Corruption	Dark fires consume your soul with strange paranoia and eyes that seem to bear into your soul
Shivers Disease	Shivers Disease is a common disease that makes the host sick with extreme vomiting,Heat sweats and Uncontrollable shivering. This disease spreads to other's through sweat.
Shrinking Sickness	Spread by certain animals and plants to protect themselves.
Sigma Virus	Tainted by the true viral form of Sigma, this behavioral disease turns Constructs violent and irrational, and in worse cases, into Sigma's puppets.
Silent Screams	Nobody can hear your suffering if you can't even speak.
Sleeping Sickness	What's a little flo-....I REFUSE TO SLEEP! IF I GO TO SLEEP I MIGHT NEVER AWAKEN!
Snow Sickness	The bane of travelers in the coldest regions.
Soot Skin	A disease that slowly ravages your skin, gradually turning it to ash.
Spawn	This will let you find your center.
Sphinx Pox	Slowly, you become a sphinx
Spore Rot	A gradual, but a fatal fungal disease.
Staphobia	An aggressive infection characterized by necrosis and cannibalistic hunger. The infectious microform of the staphobia.
Stoneheart	You feel your blood begin to thicken, and your body becomes hard to move...
Supraventricular Tachycardia (SVT)	A disorder that makes one's heart beat faster than normal.
Terrortoma	A cancerous infection that grants weaponized polyps at the cost of increased volatility. The infectious microform of the terrortoma.
The Blight	From the outer gods, down onto the mortals. May you rot away.
The Plague	A slow and painful death.
The Red Plague	A blood disease contracted from contact with vampire's minions that causes potentially causes a slow transformation into being a vampire if not cured.
The Soups	Have you ever had the displeasure of soup projecting out of both ends just because you got a little spooked?
The White Plague	Blind to all but the Ethereal Plane.
Tinnitus	A ringing in your ears and spells of deafness.
Transformational Plague	You start transforming into other creatures you've touched.
Troll Thickening	Perpetual weight gain caused by the consumption of troll meat.
Tunnel Vision	“Wait, that isn’t 5e related?”
Useful Adventurer	A disease causing creatures to become unnaturally (and painfully) useful.
Vile Polypore	This disease of fungus debilitates its host and makes them a mindless automaton before ultimate death.
Viral Bullosa	Skin becomes very delicate, causing its victim to be more easily injured.
Walter's Syndrome	A strange disease that makes you speak in a constantly angry tone.
Weaver's Fever	A flu-like disease. Annoying, but not lethal... unless you're a wizard.
Wonky Body	The afflicted’s body changes randomly, and becomes extremely awkward and possibly debilitating.
Wormification	Will you become a swarm or a single worm?
Zombie Virus	Get bit by a zombie, become a zombie

Curses

For when you want something a little more supernatural, that your paladins can be afflicted with

Curses	Summary
A Day in Seven Lives	Turns you into a completely different person each day for seven days.
Altren's Mark	You bear the cursed and blessed mark of Altren, that weakens your body.
Asmodeus Junior's Luck	cursed to have the luck of the tefling Asmodeus junior
Bad Juju	A curse that makes the "infected" clumsy and have bad luck.
Baneweaver Curse	Something made mother nature mad. You should probably find out what.
Beggar's Curse of the Sea	A certain wish that changed everything due to selfishness
Broken Halo	A curse placed on a high priest or paladin for acting against their god's will.
Crimson Curse	A vampiric curse spread from the Crimson Court
Curse of Booming Words	No matter how quietly you try to speak, your words boom thunderously.
Curse of Ill Entry	A spike of pain shoots through you each time you pass through a doorway.
Curse of Immortality	Your spirit remains forcefully bound to your body, confining it to never experience its place in the outer planes.
Curse of Incompetence	Reduce your proficiency score!
Curse of the River Goddess	A dehydrating curse created by a spiteful river goddess.
Curse of the Ultima	This curse created the first werewolf that is not a lycanthrope. Because of this curse, you, and only your type can turn people with human blood running in their veins into your kind
Devil's Cuse	You have tried to swindle a devil and failed to fulfill your end of the bargain.
Fiend Fever	*not actually a fever
Greed’s Death, Variant	Cough up gold! Could be fatal...
Jusenkyo Accursed	You have fallen into the cursed springs of the legendary training ground Jusenkyo, and now you transform whenever you come into contact with cold water.
Lost or Found	you have zero sense of direction and get lost at every minute, although sometimes you simply know the location of everything.
Nature's Rage	May you engage in brutal combat
Project G.O.R.O.	Go, Out Run, Oppress
Ragnarok Mark	You are now virtual property of the gods upon your end
Sacrosanct	Those who stand by the sword shall die by it.
Sinister Sleepwalking	If you think sleepwalking is horrible, wait til you see this.
Teleglow	The matter in your body doesn't want to stay there, and the things that shouldn't be there suddenly are
The Adventuring Curse	A curse designed to make Shawn Spellblade unstoppable. Not that he cared to be.
The Curse of Many Babies	Disrespect kids, get the opposite back.
The Stiffening	Slowly your muscles and joints harden
Trumpet's Bane	Trumpets sound nice normally, right?
VIRUS	The power to make a deity despair by sealing their power... That is VIRUS.
Witch's Curse	Fly, my pretties! Fly!
Wooden Fingers	Yes, your fingers turn into small, curly branches of a tree.

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